A character can manufacture chemicals if he/she has access to a laboratory facility. A laboratory facility costs £3 to build, or can be rented normally for around 6d per day.
Each chemical has a defined:
To make the chemical, a character must have the right ingredients available in the laboratory for the required manufacture time, and then make a dice roll using his/her Science (including making chemicals specialism) + IQ at the relevant difficulty. Success creates 1 kilogram of the chemical; failure creates nothing useful. Disastrous failure may cause a mishap (e.g. the laboratory explodes).
A character can try to reduce the time taken to make the chemical. For each day that the manufacture time is reduced (to a minimum of 1 day), the difficulty is increased by +1.
Examples of chemicals that a character could make include:
| Chemical | Ingredient cost | Manufacture time | Manufacture difficulty | Notes |
| Nerve poison (slow-acting) | 5s | 3 days | 4 | Can be smeared on weapons to cause poison damage (1 kg is enough for 30 applications) |
| Nerve poison (normal) | 10s | 6 days | 6 | |
| Nerve poison (fast-acting) | 20s | 9 days | 8 | |
| Blood agent | 3s | 2 days | 2 | Can be smeared on weapons to increase the chance of infection (1 kg is enough for 30 applications) |
| Slow poison | 8s | 4 days | 7 | Progressively poisons someone over time. 1 kg is enough to poison one person over a period of 2-3 months. |
| Antidote to a specific poison | 10s | 5 days | 6 | Automatically neutralises the specified poison. 1 kg is enough for 10 uses. |
| Greek fire grenade | 20s | 4 days | 8 | When used as a thrown weapon, acts like naphalm, sticking to the target and doing basic damage of 13 (fire damage) per combat turn (5 seconds) to the target. The flames last for 6 turns (30 seconds). |
| Methane grenade | 10s | 2 days | 5 | When set off (e.g. having been thrown), explodes causing basic damage of 10 (fire damage) to everyone in a 2 metre radius. |
| Transmutation fluid | 200s | 20 days | 15 | When used, changes up to 1 kg of any substance into any other substance (e.g. changing lead into gold). |
| Strong acid | 400s | 30 days | 12 | Can be used to dissolve through stone or metal. If used as a thrown weapon, does basic damage of 15 to target. |